POU-domain factor Brn3a regulates both distinct and common programs of gene expression in the spinal and trigeminal sensory ganglia

doi:10.1186/1749-8104-2-3

Neural Development

Volume 2

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Dykes IM
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Fedtsova N
Turner EE

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Research article

POU-domain factor Brn3a regulates both distinct and common programs of gene expression in the spinal and trigeminal sensory ganglia

S Raisa Eng , Iain M Dykes , Jason Lanier , Natalia Fedtsova and Eric E Turner

Department of Psychiatry, University of California, San Diego and VA San Diego Healthcare System, Gilman Drive, La Jolla, CA 92093-0603, USA

author email corresponding author email

Neural Development 2007, 2:3doi:10.1186/1749-8104-2-3


Published:	19 January 2007

Additional files

Additional file 1:

Differential gene expression in trigeminal and dorsal root ganglia. In situ hybridization showing transcripts differentially expressed in the trigeminal and dorsal root ganglia.

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Additional file 2:

Increased and Decreased transcripts in E13.5 DRG of Brn3a knockout mice. This shows a more complete version of the data set presented in Table 1.

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Additional file 3:

Direct comparision of altered gene expression in DRG and TG of Brn3a knockout sensory ganglia. Gene expression in the DRG is analyzed using the U74v2 array set to allow direct comparision to a prior data set for the TG.

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Additional file 4:

Dorsal root ganglia exhibit significant compensation for the loss of one Brn3a allele. Gene expression levels are compared for Brn3a wild-type, heterozygote, and knockout ganglia to demonstrate the extent to which gene dosage compensation reduces the heterozygote phenotype.

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Additional file 5:

Summary of insitu hybridization probes andLocus-ChIP oligonucleotides. Summary of insitu hybridization probes andLocus-ChIP oligonucleotides.

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