Figure 5.

Brn3a regulation of Hox gene expression in the DRG. Hox gene expression data were derived from 430A+B array data for E13.5 Brn3a wild-type (wt) and knockout (ko) DRG. Statistically significant increases (p < 0.005) in the knockout were observed for 7 anterior Hox transcripts, and significant decreases were observed (p > 0.995) for two posterior Hox transcripts (asterisks). Similar changes reached statistical significance for 5 anterior Hox genes and one posterior Hox gene in a replicate assay. HoxA7 (parentheses) did not reach statistical significance for detection, indicating high background signal in this probe set. Legend: n.g., no gene at the corresponding position in the cluster; n.d., not determined.