 Research articleAntagonism between Notch and bone morphogenetic protein receptor signaling regulates neurogenesis in the cerebellar rhombic lipRobert P Machold1 1 New York University School of Medicine Smilow Neuroscience Program Department of Otolaryngology 522 First Avenue New York, NY 10016, USA 2 New York University School of Medicine Smilow Neuroscience Program Department of Cell Biology 522 First Avenue New York, NY 10016, USA
Neural Development 2007, 2:5doi:10.1186/1749-8104-2-5
Additional filesAdditional File 1: The E10.5 isthmus and roof plate are not overtly affected by loss of Notch1. Expression analysis of fgf8, wnt1, and otx2 by in situ hybridization on sections of E10.5 control and En1cre;floxNotch1 embryos Format: PDF Size: 389KB Download file This file can be viewed with: Adobe Acrobat Reader Additional File 2: Cell death in the cerebellar primordium is not overtly increased at E12.5 upon loss of Notch1. TUNEL staining on sections of E12.5 control and En1cre;floxNotch1 embryos Format: PDF Size: 183KB Download file This file can be viewed with: Adobe Acrobat Reader Additional File 3: Notch activation induces hes1 and inhibits cath1 expression in the chick cerebellar primordium. Electroporation of Notch1 ICD in the chick cerebellar anlage results in an increase in hes1 expression and a decrease in cath1 as measured by section in situ hybridization Format: PDF Size: 213KB Download file This file can be viewed with: Adobe Acrobat Reader |
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