Identification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors

Patrick Pla¹^,2^,3 , Marie-Rose Hirsch¹^,2 , Stéphane Le Crom⁴ , Simone Reiprich¹^,2^,5 , Vincent R Harley⁶ and Christo Goridis¹^,2

¹Ecole normale supérieure, Département de Biologie, 75005 Paris, France

²CNRS, UMR8542, 75005 Paris, France

³UMR 146 Institut Curie-CNRS, Centre Universitaire, Bat. 110, 91405 Orsay cedex, France

⁴IFR36, Plate-forme Transcriptome, Ecole normale supérieure, 75005 Paris, France

⁵Institut für Biochemie, 91054 Erlangen, Germany

⁶Human Molecular Genetics Laboratory, Prince Henry's Institute of Medical Research, Clayton, Victoria 3168, Australia

author email corresponding author email

Neural Development 2008, 3:14doi:10.1186/1749-8104-3-14


Published:	19 June 2008

Additional files

Additional file 1:

Genes down-regulated in Phox2b^LacZ/LacZembryos. A list of the 51 genes that were found to be significantly down-regulated in the ventral r4 of Phox2b^LacZ/LacZembryos according to the criteria presented in Materials and methods (SAM score above 3.5). The expression of the genes written in red was tested by ISH in Phox2b^LacZ/+and Phox2b^LacZ/LacZembryos.

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Additional file 2:

Genes up-regulated in Phox2b^LacZ/LacZembryos. A list of the 23 genes that were found to be significantly up-regulated in the ventral r4 of Phox2b^LacZ/LacZembryos according to the criteria presented in Materials and methods (SAM score below -3.5). The expression of the genes written in red was tested by ISH in Phox2b^LacZ/+and Phox2b^LacZ/LacZembryos.

Format: DOC Size: 121KB Download file

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