Figure 1.

Expression patterns of a subset of genes down-regulated in ventral r4 of Phox2b^LacZ/LacZ embryos. (a-h) In situ hybridizations on transverse sections of ventral r4 of Phox2b^LacZ/+ (a, c, e, g) or Phox2b^LacZ/LacZ (b, d, f, h) E10.5 mouse embryos. DIG-labeled riboprobes recognizing App (a, b), Mapk8 (c, d), Nfl (e, f) and Gap43 (g, h) mRNA were used. The normally Phox2b-expressing region as visualized by anti-beta-galactosidase staining on adjacent sections is delimited by gray bars.