Examination of lateralized neuron soma sizes in the head ganglia of C. elegans. (A) Schematic representation of the C. elegans head, showing the general symmetric morphology of ASE neurons overlaid with asymmetric function. (B) Example of the expression pattern of bilaterally expressed che-1prom::gfp. (C) Individual measurements of soma size for several head neuron pairs. Measurements are shown as two open circles; lines connect each individual. Averages of each cell type are indicated as horizontal bars. The AWC neurons, in addition to being measured as a left/right pair, were measured as an AWCon/AWCoff pair in separate animals, using str-2::gfp (kyIs140) for AWCon/AWCoff identification. See Materials and methods for all reporters used. **P < 0.01; ns, not significant. (D) Averages of left/right (or AWCon/AWCoff) ratios, generated from the data shown in (C). The dashed line is at a ratio of 1, which indicates the left and right cells are of equivalent volume. Error bars are standard error of the mean.
Goldsmith et al. Neural Development 2010 5:33 doi:10.1186/1749-8104-5-33