Protein sequence alignment of X. laevis insulin receptor IR1 with different species. Amino acid sequence derived from Xenopus IR1 was aligned with rat, mouse and human insulin receptor protein sequences with the ClustalW algorithm. Schematic drawing of the alignment identities (percentages) in different functional domains of insulin receptor. Note that the predicated Xenopus kinase domain shares the highest identity with other species compared to other domains.
Chiu and Cline Neural Development 2010 5:7 doi:10.1186/1749-8104-5-7