Open Access Highly Accessed Research article

Coordinated trafficking of synaptic vesicle and active zone proteins prior to synapse formation

Luke AD Bury1 and Shasta L Sabo1,2*

1 Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, 44106, USA

2 Department of Neuroscience, Case Western Reserve University School of Medicine, Cleveland, Ohio, 44106, USA

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Neural Development 2011, 6:24 doi:10.1186/1749-8104-6-24

Published: 10 May 2011

Additional files

Additional file 1:

Movie 1. Movie showing STV and PTV movements in the same axon. The top three panels show bassoon, synaptophysin and the transmitted light image, respectively. The bottom panel corresponds to the overlay of all three. STVs and PTVs can be seen moving together and pausing at the same sites. The yellow boxes highlight areas in which STVs and PTVs clearly move together. The axon itself does not move significantly during the imaging. Times are indicated at the bottom left.

Format: AVI Size: 2.3MB Download file

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