The E3 ubiquitin ligase skp2 regulates neural differentiation independent from the cell cycle.

Depletion of the cell-cycle inhibitor p27(Xic1) impairs neuronal differentiation and increases the number of ElrC(+) progenitor cells in Xenopus tropicalis.

Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling.

Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins.

PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2).

Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation.

Distinct effects of XBF-1 in regulating the cell cycle inhibitor p27(XIC1) and imparting a neural fate.

The cdk inhibitor p27Xic1 is required for differentiation of primary neurones in Xenopus.

Tuberin binds p27 and negatively regulates its interaction with the SCF component Skp2.

Regulation of the cell cycle inhibitor p27 and its ubiquitin ligase Skp2 in differentiation of human embryonic stem cells.

Notch targets the Cdk inhibitor Xic1 to regulate differentiation but not the cell cycle in neurons.

The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells.

Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells.

The COP9 signalosome regulates Skp2 levels and proliferation of human cells.

A single cdk inhibitor, p27Xic1, functions beyond cell cycle regulation to promote muscle differentiation in Xenopus.

Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase.

Regulation of SCF(SKP2) ubiquitin E3 ligase assembly and p27(KIP1) proteolysis by the PTEN pathway and cyclin D1.

Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression.

Geminin regulates neuronal differentiation by antagonizing Brg1 activity.

Cardiac differentiation in Xenopus requires the cyclin-dependent kinase inhibitor, p27Xic1.